Our research group at IIT Hyderabad pursues problems in the domains of polymeric biomaterials and pharmaceutical soft matter. We investigate process-structure-property relations in polymers with the goal of employing them in drug carrier design. A major focus in our lab is electrospinning, which we holistically investigate to gain insights into fiber and particle formation. We use this understanding to design non-woven fibrous meshes and powders for the regulated release of poorly soluble drugs. We study the physics of electrospinning, investigate the thermodynamic properties of drug-polymer systems, elucidate drug release mechanisms and engineer technologies for the concurrent co-release of drug and protein. We also develop approaches to improve the stability of co-amorphous drug mixtures by leveraing molecular interactions that lead to the enhancement of glass transition temperatures. In close collaboration with biologists, we deploy drug-loaded materials to target chronic inflammation.
|
contact
#321, chemical engineering, iit hyderabad, iith main road, near nh-65, kandi, sangareddy, telangana 502285 samavedi [at] che.iith.ac.in 040-23018189 (lab) |
|
