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Our lab at IIT Hyderabad pursues problems in the broad domains of polymeric biomaterials and pharmaceutical soft matter. We investigate structure-property-processing relationships in polymers with the goal of employing them in controlled release applications. A major focus in our lab is polymer electrospinning, which we holistically investigate to gain insights into fiber formation. We use this understanding to design non-woven fibrous meshes for the regulated release of small molecule drugs/proteins. We investigate physico-chemical properties of electrospun carriers, elucidate release mechanisms and build technologies for achieving combination therapy using multiple therapeutics. We also work with biologists to deploy such functionalized materials in degenerative conditions associated with chronic inflammation. More recently, we have begun taking an active interest in improving the physical stability of drug formulations and developing design rules for amorphous solid dispersions & co-amorphous drug mixtures.
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contact
#321, chemical engineering, block a, iit hyderabad, iith main road, near nh-65, kandi, sangareddy, telangana 502285 samavedi [at] che.iith.ac.in 040-23018189 (lab) |
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